에 대한 최신 뉴스 OSR Holdings (NASDAQ:OSRH) 주식

OSR Holdings

OSR Holdings Inc is a healthcare company dedicated to healthcare outcomes and improving the quality of life for people and their families. It builds and develops a robust portfolio of potentially transformative therapies and healthcare solutions. The business of the company includes developing oral immunotherapies for the treatment of cancer, developing design-augmented biologics for age-related and other degenerative diseases, and neurovascular intervention medical device and systems distribution in Korea.

OSR Holdings Inc

<a href="https://www.sec.gov/ix?doc=/Archives/edgar/data/1870404/000121390025050055/ea0244195-8k_cero.htm" title="https://www.sec.gov/ix?doc=/Archives/edgar/data/1870404/000121390025050055/ea0244195-8k_cero.htm">https://www.sec.gov/ix?doc=/Archives/edgar/data/1870404/000121390025050055/ea0244195-8k_cero.htm</a>

News

Management

CERO

CERo Therapeutics Appoints Chris Ehrlich As CEO

At the annual meeting of stockholders of Amaze Holdings, Inc., a Nevada corporation (the "Company"), to be held on June 12, 2025 (the "Annual Meeting"), the Company's stockholders will vote to approve, among other things, a proposal to authorize a reverse stock split of the Company's issued and outstanding common stock, par value $0.001 per share (the "Common Stock"), at a ratio in the range of 1-for-10 and 1-for-50, with such ratio and implementation and timing of the reverse stock split to be determined in the discretion of the Company's Board of Directors (the "Reverse Stock Split Proposal").
&nbsp;
On June 2, 2025, the Company's Board of Directors determined to effect a 1-for-23 reverse stock split of the Company's issued and outstanding Common Stock effective at 5:00 p.m. Eastern time on June 12, 2025 (the "Effective Time"), subject to stockholder approval of the Reverse Stock Split Proposal at the Annual Meeting.
&nbsp;
Upon stockholder approval of the Reverse Stock Split Proposal at the Annual Meeting, immediately following the conclusion of the Annual Meeting on June 12, 2025, the Company will file a certificate of amendment to its Articles of Incorporation to effect the 1-for-23 reverse stock split at the Effective Time. The Company's Common Stock is expected to begin trading on a reverse stock split adjusted basis on the NYSE American at market open on June 13, 2025.
&nbsp;
The reverse stock split is primarily intended to increase the Company's per share market price of its Common Stock to meet the $3.00 per share minimum bid price requirement of the NYSE American Company Guide. The Company's Common Stock will continue to trade on the NYSE American under the trading symbol "AMZE," but will trade under the following new CUSIP number: 35804X 200.

Stock Split

AMZE

Amaze Holdings To Implement 1-For-23 Reverse Stock Split, Aiming To Regain NYSE American Compliance; Stock To Begin Trading On Split-Adjusted Basis June 13, 2025

On May 28, 2025 (the "Closing Date"), our Avis Budget Rental Car Funding (AESOP) LLC subsidiary ("ABRCF") issued $736.5 million of asset-backed securities with a maturity of three years and five years, respectively, comprised of $199.0 million aggregate principal amount of Series 2025-1 4.80%, Class A notes, $29.75 million aggregate principal amount of Series 2025-1 5.24%, Class B notes, $21.25 million aggregate principal amount of Series 2025-1 5.87%, Class C notes and $33.29 million aggregate principal amount of Series 2025-1 7.48%, Class D notes, as well as $318.4 million aggregate principal amount of Series 2025-2 5.12%, Class A notes, $47.6 million aggregate principal amount of Series 2025-2 5.51%, Class B notes, $34.0 million aggregate principal amount of Series 2025-2 6.24%, Class C notes and $53.26 million aggregate principal amount of Series 2025-2 7.84%, Class D notes. The Class D notes were retained by ABRCF and may be sold on a future date. ABRCF also issued $15.6 million aggregate principal amount of Series 2025-1 9.424%, Class R notes and $25.0 million aggregate principal amount of Series 2025-2 9.795%, Class R notes, each of which are subordinated to the Class A notes, the Class B notes, the Class C notes and the Class D notes of the respective Series, and which were issued to comply with applicable U.S. risk retention rules. The Class R notes are held by our AESOP Leasing L.P. subsidiary. The notes were issued under the Series 2025-1 Supplement, dated as of the Closing Date, between ABRCF and The Bank of New York Mellon Trust Company, N.A., as trustee and Series 2025-1 Agent (the "Series 2025-1 Supplement"), to the Second Amended and Restated Base Indenture, dated as of June 3, 2004 (as amended, the "Base Indenture") and the Series 2025-2 Supplement, dated as of the Closing Date, between ABRCF and The Bank of New York Mellon Trust Company, N.A., as trustee and Series 2025-2 Agent (the "Series 2025-2 Supplement"), to the Base Indenture, respectively.

Financing

Avis Budget Rental Car Funding (AESOP) Issues $736.5M In Asset-Backed Securities Across Two Series With Maturities Of 3 And 5 Years

Earnings

Earnings Misses

NCNA

NuCana Q1 EPADS $(0.75)

BSII

Black Spade Acquisition II To Voluntarily Delist From Nasdaq Upon Consummation Of Pending Business Combination With The Generation Essentials Group

Donaldson Appoints Richard Lewis Chief Operating Officer, Effective August 1, 2025

Blackstone (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BX#NYSE">BX</a>) has outperformed the market over the past 10 years by 2.12% on an annualized basis producing an average annual return of 13.13%. Currently, Blackstone has a market capitalization of $107.39 billion. 
Buying $100 In BX: If an investor had bought $100 of BX stock 10 years ago, it would be worth $337.69 today based on a price of $138.92 for BX at the time of writing.
<h3>Blackstone's Performance Over Last 10 Years</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1748895316_0.png" alt="comp_fig" />
Finally -- what's the point of all this? The key insight to take from this article is to note how much of a difference compounded returns can make in your cash growth over a period of time.
This article was generated by Benzinga's automated content engine and reviewed by an editor.

Trading Ideas

$100 Invested In This Stock 10 Years Ago Would Be Worth This Much Today

Both Leading Proxy Advisory Firms Recommend Shareholders Vote AGAINST Chairman George Mayes, Jr., Director Javier Polit and Director Laurie Tucker
Glass Lewis Confirms That These Three Directors Are Unlikely to be "Procedurally Accretive" to the Ongoing Strategic Review
Ancora Holdings Group, LLC (together with its affiliates, "Ancora" or "we"), a significant shareholder of Forward Air Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FWRD#NASDAQ">FWRD</a>) ("Forward Air" or the "Company"), today announced that a second independent proxy advisory firm, Glass, Lewis &amp; Co. ("Glass Lewis"), has joined Institutional Shareholder Services Inc. ("ISS"), in recommending that Forward Air shareholders vote AGAINST the reelection of three members of the Board of Directors (the "Board") at the 2025 Annual Meeting of Shareholders: (1.) George S. Mayes, Jr., (2.) Javier Polit and (3.) Laurie A. Tucker.
In its report, Glass Lewis states the following regarding the case for removing these directors from the Board:1
<ul>
<li>"Are legacy directors who served during the questionable pursuit, fumbled execution and to-date maladroit implementation of the Omni deal credibly positioned to oversee Forward's current assessment of value-maximizing opportunities? We believe the answer is a firm no."</li>
<li>"[I]nvestors do not have clear and compelling cause to believe Messrs. Mayes and Polit and Ms. Tucker are likely to be procedurally accretive and indeed have ample cause to conclude they have not been effective in preserving and enhancing shareholder value, particularly in the context of transformative transactions."</li>
</ul>

FWRD

Both ISS And Glass Lewis Urge Forward Air Shareholders To Vote Against Chairman George Mayes Jr., Directors Javier Polit And Laurie Tucker, Citing Poor Oversight Of Omni Deal And Lack Of Value-Enhancing Contributions

BYFC

Broadway Financial Announces Nasdaq Noncompliance Notification

– Results from Phase 1b clinical trial evaluating onvansertib + paclitaxel for metastatic triple negative breast cancer demonstrated 40% objective response rate –
– The trial evaluated three doses of onvansertib in combination with paclitaxel, and objective responses were observed only at the highest dose of onvansertib –
– The combination was well-tolerated and demonstrated a safe and manageable toxicity profile –
SAN DIEGO, June 02, 2025 (GLOBE NEWSWIRE) -- Cardiff Oncology, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CRDF#NASDAQ">CRDF</a>), a clinical-stage biotechnology company leveraging PLK1 inhibition to develop novel therapies across a range of cancers, today announced positive data from an investigator-initiated Phase 1b clinical trial evaluating onvansertib in combination with paclitaxel in patients with metastatic triple-negative breast cancer (mTNBC) at the American Society of Clinical Oncology (ASCO) Annual Meeting, taking place from May 30-June 3, 2025, in Chicago, Illinois.

CRDF

Cardiff Oncology Presents Data From Investigator-Initiated Phase 1b Clinical Trial Evaluating Onvansertib In Combination With Paclitaxel In Patients With mTNBC At 2025 ASCO Annual Meeting

ENSG

The Ensign Group Acquires Nursing Facility In California; Financial Terms Not Disclosed

Dividends

EPRT

Essential Properties Realty Trust Increases Quarterly Dividend From $0.295 To $0.30/Share

First-line maintenance combination therapy reduced the risk of disease progression or death by 46%, with a median overall survival of 13.2 months vs 10.6 months&nbsp;for atezolizumab alone from the point of randomization
First Phase 3 study to demonstrate statistically significant and clinically meaningful improvements in both progression-free and overall survival in ES-SCLC first-line maintenance
Results presented at the ASCO 2025 Annual Meeting and simultaneously published in The Lancet
Jazz to host investor webcast on Tuesday, June 10 to review Zepzelca data
For U.S. media and investors only
DUBLIN, June 2, 2025 /PRNewswire/ -- Jazz Pharmaceuticals plc&nbsp;(NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/JAZZ#NASDAQ">JAZZ</a>) today announced positive results from the Phase 3 IMforte study of Zepzelca&#xAE; (lurbinectedin) in combination with atezolizumab (Tecentriq&#xAE;) as a first-line maintenance treatment for people with extensive-stage small cell lung cancer (ES-SCLC), following induction therapy with carboplatin, etoposide and atezolizumab. The study met both primary endpoints, demonstrating statistically significant improvements in progression-free survival (PFS) and overall survival (OS) compared to atezolizumab alone.
IMforte is the first global Phase 3 trial to demonstrate clinically meaningful PFS and OS benefits in the first-line maintenance setting for ES-SCLC and supports maintenance therapy with Zepzelca&nbsp;plus atezolizumab as a new standard of care for patients. The data were presented today in an oral session at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago and published simultaneously in <a href="https://c212.net/c/link/?t=0&amp;l=en&amp;o=4439716-1&amp;h=26984983&amp;u=https%3A%2F%2Fwww.thelancet.com%2Fjournals%2Flancet%2Farticle%2FPIIS0140-6736(25)01011-6%2Ffulltext&amp;a=The+Lancet">The Lancet</a>. Data from the trial served as the basis for the supplemental New Drug Application (sNDA) submission to the U.S. Food and Drug Administration&nbsp;(FDA).
Following induction therapy with carboplatin, etoposide and atezolizumab, patients who did not have disease progression were randomized to receive Zepzelca plus atezolizumab or atezolizumab alone. From the point of randomization, the median PFS was 5.4 months for the Zepzelca plus atezolizumab combination versus 2.1 months for atezolizumab alone (stratified HR = 0.54, 95% CI: 0.43–0.67; p &lt; 0.0001), and median OS was 13.2 months versus 10.6 months (stratified hazard ratio [HR] = 0.73; 95% CI: 0.57–0.95; p = 0.0174). The combination reduced the risk of disease progression or death by 46% and the risk of death by 27% compared to atezolizumab alone. The Zepzelca plus atezolizumab combination had no new or unexpected safety signals.

Biotech

General

JAZZ

Jazz Pharmaceuticals Announces Phase 3 IMforte Trial Results Showing Zepzelca Plus Atezolizumab First-Line Maintenance Therapy Reduces Disease Progression Risk By 46% And Extends Median Overall Survival To 13.2 Months In ES-SCLC; Data Presented At ASCO 2025 And Published In The Lancet, Supporting New Standard Of Care And FDA sNDA Submission

Overall pan-cancer sensitivity of 94% and specificity of 100%, with analytical detection down to 1 PPM
<a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.natera.com&amp;esheet=54263860&amp;newsitemid=20250602831213&amp;lan=en-US&amp;anchor=Natera%2C+Inc.&amp;index=1&amp;md5=7205b90051b2da6a2abf789e99afd34b">Natera, Inc.</a> (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NTRA#NASDAQ">NTRA</a>), a global leader in cell-free DNA and precision medicine, announced results from a large-scale pan-cancer study of its Signatera Genome assay, which was presented today, June 2nd, at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting.
The study analyzed the performance of Signatera Genome in a cohort of 392 patients (&gt; 2,600 plasma samples) across five different tumor types (breast cancer, non-small cell lung cancer, melanoma, renal cell carcinoma, and colorectal cancer). Key results included:
<ul>
<li>Excellent pan-cancer performance: Signatera Genome demonstrated overall longitudinal sensitivity of 94% and specificity of 100% across 5 cancer types. Longitudinal sensitivity was 100% in lung cancer and renal cancer, and post-surgical landmark sensitivity was over 70% in both lung cancer and breast cancer.</li>
<li>Ultrasensitive detection: In the surveillance setting, nearly 50% of Signatera-positive cases were detected in the ultra-sensitive range (≤100 parts per million).</li>
<li>Highly predictive of long-term outcomes: In the pancancer cohort, patients who tested Signatera-negative had excellent prognosis, with 100% distant relapse-free survival (DRFS) at 12 months and 99% at 24 months. In contrast, Signatera-positive patients faced a markedly higher risk of recurrence, with DRFS dropping to 41% at 12 months and just 14% at 24 months.</li>
<li>Extended lead times: Signatera Genome detected recurrence 3 months earlier, on average, compared to the Signatera Exome assay.</li>
<li>Demonstrates Signatera's potential to identify which patients may benefit from adjuvant therapy: Among Signatera-positive patients, those who received adjuvant therapy had significantly improved outcomes, with a 12-month DRFS of 83% compared to 49% for those who did not receive therapy. For Signatera-negative patients, there was no meaningful benefit from adjuvant therapy with a 12-month DRFS of 93% (treated) vs. 98% (observation).</li>
</ul>

NTRA

Natera Presents Results From Large-Scale Pan-Cancer Study Of Signatera Genome Assay At 2025 ASCO Annual Meeting

Empowering enterprises across industries to build and deploy secure, compliant AI agents and applications with Snowflake Postgres, powered by Crunchy Data's enterprise-grade PostgreSQL
<a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.snowflake.com%2F&amp;esheet=54263223&amp;newsitemid=20250602455530&amp;lan=en-US&amp;anchor=Snowflake&amp;index=1&amp;md5=ba422637d7f8c26f397a956c82baaa6a">Snowflake</a> (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SNOW#NYSE">SNOW</a>), the AI Data Cloud company, today announced at its annual user conference, <a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.snowflake.com%2Fen%2Fsummit%2F&amp;esheet=54263223&amp;newsitemid=20250602455530&amp;lan=en-US&amp;anchor=Snowflake+Summit+2025&amp;index=2&amp;md5=2df932361745e54fc8138426404cb066">Snowflake Summit 2025</a>, its intent to acquire Crunchy Data, a leading provider of trusted open source Postgres technology and products. This acquisition will bring Snowflake Postgres, the AI-ready, enterprise-grade and developer-friendly PostgreSQL database to the AI Data Cloud, enabling developers with the full power of Postgres while providing the uncompromising governance, security and operational standards essential for building and running mission-critical AI applications.

SNOW

Snowflake To Acquire Crunchy Data; Terms Undisclosed

VRSN

VeriSign Executive Vice President And Chief Financial Officer George E. Kilguss III Retired From The Company Effective May 31, 2025

First Quarter of Fiscal Year 2026 Financial Outlook
<ul>
<li>Revenue is expected to be between $185.0 million and $195.0 million</li>
<li>GAAP gross margin is expected to be between 63.4% and 65.4%, and non-GAAP gross margin is expected to be between 64.0% and 66.0%</li>
<li>GAAP operating expenses are expected to be between $88.3 million and $90.3 million, and non-GAAP operating expenses are expected to be between $54.0 million and $56.0 million</li>
</ul>

Guidance

CRDO

Credo Technology Group Sees Q1 Sales $185.000M-$195.000M vs $167.83M Est

Credo Technology Group (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CRDO#NASDAQ">CRDO</a>) reported quarterly earnings of $0.35 per share which beat the analyst consensus estimate of $0.28 by 25 percent. This is a 400 percent increase over earnings of $0.07 per share from the same period last year. The company reported quarterly sales of $170.03 million which beat the analyst consensus estimate of $162.96 million by 4.34 percent. This is a 179.73 percent increase over sales of $60.78 million the same period last year.

Earnings Beats

Credo Technology Group Q4 Adj. EPS $0.35 Beats $0.28 Estimate, Sales $170.03M Beat $162.96M Estimate

<a href="https://c212.net/c/link/?t=0&amp;l=en&amp;o=4440397-1&amp;h=3926069017&amp;u=https%3A%2F%2Fwww.trevitherapeutics.com%2F&amp;a=Trevi+Therapeutics%2C+Inc">Trevi Therapeutics, Inc</a>. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TRVI#NASDAQ">TRVI</a>), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio&#x2122; (oral nalbuphine ER) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF) and in patients with refractory chronic cough (RCC), today announced that it has commenced an underwritten public offering of $100,000,000 of shares of its common stock. All of the shares in the offering are being offered by Trevi. In addition, Trevi expects to grant the underwriters a 30-day option to purchase up to an additional $15,000,000 of the shares of its common stock sold in the public offering at the public offering price, less underwriting discounts and commissions.

Offerings

TRVI

Trevi Therapeutics Launches $100M Public Offering Of Common Stock To Support Development Of Haduvio For Chronic Cough In IPF And RCC

<a href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.personalis.com%2F&amp;esheet=54263877&amp;newsitemid=20250602947359&amp;lan=en-US&amp;anchor=Personalis%2C+Inc.&amp;index=1&amp;md5=3e4c9e0b952c4b9b34435ce78c8a2a75">Personalis, Inc.</a> (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PSNL#NASDAQ">PSNL</a>), a leader in advanced genomics for precision oncology, announced the presentation of new clinical results from the PREDICT DNA and SCANDARE studies highlighting the capabilities of its ultrasensitive NeXT Personal circulating tumor DNA (ctDNA) blood test for monitoring and predicting neoadjuvant therapy (NAT) response in triple negative breast cancer (TNBC), one of the most aggressive types of breast cancer.
Results from the PREDICT DNA study were presented yesterday by Dr. Natasha Hunter, MD, University of Washington, at the American Society for Clinical Oncology (ASCO) 2025 Annual Meeting in Chicago in an oral presentation titled "Circulating tumor DNA, pathologic response after neoadjuvant therapy, and survival: First results from TBCRC 040 (the PREDICT DNA trial)."
Key findings included:
ctDNA status after completion of NAT (post-NAT) was highly prognostic for relapse-free survival (RFS). Patients with ctDNA detected post-NAT were ~10 times more likely to relapse than patients who were ctDNA negative. Detection of ctDNA post-NAT was more predictive of recurrence than pCR. Patients who did not have detectable post-NAT ctDNA had excellent outcomes regardless of pathologic response. Preliminary analyses indicate that patients who had post-surgical ctDNA detected were &gt;85 times more likely to experience disease recurrence. 48% of post-NAT ctDNA detections were &lt;100 PPM, highlighting the importance of NeXT Personal's ultrasensitive performance. Overall, the results suggest that ultrasensitive ctDNA detection in patients with TNBC after completion of NAT and prior to surgery may be used as a prognostic marker, independent of pCR, to guide clinical decision making for additional adjuvant therapies.
 &nbsp;

PSNL

Personalis Presents New Clinical Results From PREDICT DNA And SCANDARE Studies Highlighting Capabilities Of Ultrasensitive NeXT Personal ctDNA Blood Test For Monitoring And Predicting NAT Response In TNBC

Press Releases

OSR Holdings Appoints Dr. Constance Höfer as Chief Scientific Officer

Vaximm AG, an OSR Company, Announces Results from Phase 2a Trial of VXM01 and Avelumab Combination Therapy in Glioblastoma

Driving the Future of Healthcare HIT, OSRH, THTX, LPTX, CSDX, Innovations in Health Insurance, Virtual Care, Oncology, and Chronic Disease Treatment

OSR Holdings, Inc. (NASDAQ: OSRH) Enters Into $80 Million Common Stock Purchase Agreement With White Lion GBM Innovation Fund, With An Eye Towards Leveraging Innovate GBM's Non-Profit Ecosystem to Accelerate Glioblastoma Therapies

$2 Stocks to Watch: PNPN.V, TIVC, APVO, OSRH, PRSO Biotech Breakthroughs, MedTech Momentum Metallic Metals Power Play & Signal Innovation

Darnatein, an OSR Company, Broadens Intellectual Property Protection for Innovative Osteoarthritis Treatment Technology

Darnatein to Present at 14th International BMP Conference Highlighting Advances in Regenerative Biologics

Fintech

OSR Holdings, BCM Europe, and Taekwondo Cooperative Announce Strategic MOU to Launch Blockchain-Based OSRH Token

Comments

OSR Holdings

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