Spruce Biosciences Market Sentiment

Spruce Biosciences Inc

SPRBNASDAQ

Trade with Public

$39.65

N/A

$39.65

N/A

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Spruce Biosciences Market Sentiment

Market sentiment signals for Spruce Biosciences (SPRB): analyst consensus, short interest, options flow and insider activity.

Key Signals

Analyst Consensus▲ Buy

Short Interest▼ 15.2% short float

Options Flow— N/A

Insider Activity— N/A

Analyst Consensus

Buy

14 analysts

Options Flow (P/C)

—

Avg Consensus PT

$156

+293.6%

Highest Price Target

$283

+613.7%

Oppenheimer

Lowest Price Target

$38

-5.4%

RBC Capital

Short Interest

15.2%

Rising — Bearish

Insider Activity (30d)

—

Short Interest — % of Float

Recent Analyst Actions

Date	Firm	Analyst & Accuracy	Upside / Downside	PT Change	Action	Rating
Sep 24, 2026	Citizens	Jonathan Wolleben—	+263.2%	$144 → $144	Maintained	Market Outperform
Sep 17, 2026	Lake Street	Daniel Brims—	+275.8%	$149	Initiate	Buy
Aug 17, 2026	Guggenheim	Debjit Chattopadhyay—	+162.3%	$123 → $104	Maintained	Buy
Aug 13, 2026	Citizens	Jonathan Wolleben—	+263.2%	$150 → $144	Maintained	Market Outperform
Jul 13, 2026	B. Riley Securities	Madison El-Saadi—	+303.5%	$160	Initiate	Buy
Jun 16, 2026	Guggenheim	Debjit Chattopadhyay—	+210.2%	$123	Initiate	Buy
Jun 9, 2026	Jones Trading	Catherine Novack—	+240.5%	$135	Initiate	Buy
Jun 1, 2026	HC Wainwright & Co.	Raghuram Selvaraju—	+278.3%	$200 → $150	Maintained	Buy
May 14, 2026	Citizens	Jonathan Wolleben—	+278.3%	$170 → $150	Maintained	Market Outperform
Apr 27, 2026	Craig-Hallum	Albert Lowe—	+253.1%	$140	Initiate	Buy
Mar 10, 2026	Citizens	Jonathan Wolleben—	+328.8%	$180 → $170	Maintained	Market Outperform
Mar 10, 2026	HC Wainwright & Co.	Raghuram Selvaraju—	+404.4%	$200 → $200	Maintained	Buy
Feb 19, 2026	HC Wainwright & Co.	Raghuram Selvaraju—	+404.4%	$220 → $200	Maintained	Buy
Dec 23, 2025	Oppenheimer	Leland Gershell—	+613.7%	$283	Initiate	Outperform
Dec 22, 2025	HC Wainwright & Co.	Raghuram Selvaraju—	+454.9%	$220	Assumes	Buy
Dec 3, 2025	Leerink Partners	Joseph Schwartz—	+303.5%	$160	Upgrade	Market Perform→Outperform
Nov 11, 2025	Citizens	Jonathan Wolleben—	+553.2%	$254 → $259	Maintained	Market Outperform
Oct 28, 2025	JMP Securities	Jonathan Wolleben—	+540.6%	$254	Upgrade	Market Perform→Market Outperform
Oct 21, 2025	Leerink Partners	Joseph Schwartz—	+303.5%	$10 → $160	Maintained	Market Perform
Apr 16, 2025	RBC Capital	Gregory Renza—	-98.7%	$2 → $1	Maintained	Sector Perform
Dec 16, 2024	HC Wainwright & Co.	Raghuram Selvaraju—	—	—	Maintained	Neutral
Dec 12, 2024	Guggenheim	Evan Wang—	—	—	Maintained	Neutral
Dec 11, 2024	JMP Securities	Jonathan Wolleben—	-92.4%	$3 → $3	Downgrade	Market Outperform→Market Perform
Dec 11, 2024	RBC Capital	Gregory Renza—	-96.2%	$2 → $2	Maintained	Sector Perform
Dec 11, 2024	Oppenheimer	Hartaj Singh—	—	—	Downgrade	Outperform→Perform