옵션 체인은 다양한 행사가격과 만기일에 대한 Brighthouse Finl의 주식 옵션 주요 데이터를 보여줍니다. 트레이더들은 이 정보를 사용하여 잠재적 거래를 분석하고 Brighthouse Finl에 대한 시장 심리를 평가합니다..

Brighthouse Finl (NASDAQ:BHF) 주식, 옵션 체인

BRIGHTHOUSE FINANCIAL INC

Brighthouse Finl

Brighthouse Financial Inc is a United States-based provider of annuity products and life insurance through independent distribution channels and marketing arrangements with distribution partners. Its segments are Annuities, Life, Run-off and Corporate and Other. It derives a majority of the revenue from the Annuities segment which includes variable, fixed, index-linked, and income annuities. The life segment includes variable, term, universal, and whole life policies.

Brinker

Equities

Mid Cap

News

Movers

Trading Ideas

AKRO

Brighthouse Financial, Inc. - Common Stock

Hims & Hers Health, Inc. Class A Common Stock

HIMS

SGRY

VIAV

이 10개 중형주는 지난주 최고의 성과를 거두었다. 그것들이 당신의 포트폴리오에 있나요? 1. 아케로 테라퓨틱스(NASDAQ:AKRO)의 주가는 회사가 에프룩시퍼민(Efruxifermin)에 대한 SYMMETRY 2B상 연구의 96주차 예비 결과를 보고한 후 주가는 106.57% 급등했다. 몇몇 애널리스트들이 목표 주가를 상향 조정했다.

아케로 테라퓨틱스, 브링커 인터내셔널, 비아비 등 지난주 최대 상승한 중형주 (1월 27일-1월 31일)

Brighthouse Financial Inc

Brighthouse Financial, Inc. - Junior Subordinated Debentures due 2058

Brighthouse Financial, Inc. - Depositary shares each representing a 1/1,000th Interest in a Share of 4.625% Non-Cumulative Preferred Stock, Series D

Brighthouse Financial, Inc. - depositary shares, each representing a 1/1,000th interest in a share of 5.375% Non-Cumulative Preferred Stock, Series C

Brighthouse Financial, Inc. - Depositary Shares, each representing a 1/1,000th interest in a share of 6.750% Non-Cumulative Preferred Stock, Series B

Brighthouse Financial, Inc. - Depositary Shares 6.6% Non-Cumulative Preferred Stock, Series A

WIIM

QNTM

QNTM stock has given up its prior gain. Quantum Biopharma shares were trading higher after the company announced it purchased $1 million worth of bitcoin and other cryptocurrencies as part of its digital asset strategic efforts.

Evercore ISI Group analyst David Raso maintains ESAB (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/ESAB#NYSE">ESAB</a>) with a In-Line and raises the price target from $120 to $125.

Price Target

Analyst Ratings

ESAB

Evercore ISI Group Maintains In-Line on ESAB, Raises Price Target to $125

TXNM Energy, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/TXNM#NYSE">TXNM</a>) shares are trading higher premarket on Monday after the company agreed to be acquired by Blackstone Infrastructure for <a target="_blank" href="https://www.benzinga.com/pressreleases/25/05/n45489413/txnm-energy-enters-agreement-to-be-acquired-by-blackstone-infrastructure" rel="noreferrer noopener">$61.25 per share in cash at closing</a>.
The acquisition price represents a 23.0% premium over TXNM Energy&#8217;s unaffected 30-day volume weighted average price (VWAP) as of March 5, 2025, the day before media reports of a potential acquisition.
This transaction reflects a total enterprise value of $11.5 billion, which includes net debt (excluding securitization debt) and preferred stock.
Also Read: <a target="_blank" href="https://www.benzinga.com//node/45473816" rel="noreferrer noopener">George Soros Loads Up On First Solar Calls: What Does He Know That Wall Street Doesn&#8217;t?</a>
Blackstone Infrastructure is also making a $400 million investment through a private placement agreement, purchasing 8 million newly issued shares of TXNM Energy common stock at $50 per share to support TXNM Energy&#8217;s growth plans. This issuance is expected to be completed in June 2025.
TXNM Energy anticipates issuing an additional $400 million of equity before the transaction closes to further support its growth. The transaction is being funded through equity and the assumption of existing debt, with no new debt expected to be issued as a result of the acquisition.
TXNM Energy&#8217;s Board of Directors has unanimously approved the transaction, which is estimated to close in the second half of 2026, pending shareholder and regulatory approvals.
TXNM Energy shareholders can anticipate continued dividend payments through the transaction&#8217;s closing, subject to the Board of Directors&#8217; approval.
Upon closing the transaction, Pat Collawn will step down as Executive Chair. Notably, Pat Collawn transitioned from the current Chief Executive Officer&nbsp;to Executive Chair, <a target="_blank" href="https://www.benzinga.com/pressreleases/25/05/n45401627/txnm-energy-announces-executive-leadership-transition-of-pat-collawn-to-executive-chair-don-tarry-" rel="noreferrer noopener">effective&nbsp;July 1, 2025</a>.&nbsp;
Don Tarry will assume responsibility for the ongoing operations of TXNM Energy as President and CEO.
Pat Collawn said, &#8220;Our successes at TXNM Energy have stemmed from a deliberate approach to investing in PNM and TNMP in a manner aligned with the priorities of our customers and communities. We&#8217;ve integrated new resources to supply over two-thirds of PNM electricity needs with carbon-free energy and supported double-digit demand growth at TNMP.&#8221;
Investors can gain exposure to the stock via Virtus Reaves Utilities ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/UTES#NYSE">UTES</a>) and Tema Electrification ETF (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VOLT#NASDAQ">VOLT</a>).
Price Action: TXNM shares are up 9.23% at $57.76 premarket at the last check on Monday.
Read Next:
<ul class="wp-block-list">
<li><a href="https://www.benzinga.com//node/44525929" target="_blank" rel="noreferrer noopener">&#8216;Our GPUs Are Melting,&#8217; OpenAI&#8217;s Altman Warns — Could US Natural Gas Power AI Revolution?</a></li>
</ul>
Image via Shutterstock

TXNM

UTES

VOLT

Why Is TXNM Energy Stock Soaring On Monday?

It's downgrade déjà vu. Late Friday, after Wall Street had already packed up for the weekend, Moody's quietly dropped the hammer: the U.S. just got its <a href="https://www.benzinga.com/news/econ-s/25/05/45479078/moodys-downgrades-us-credit-rating-over-debt-deficit-concerns">credit rating cut from Aaa to Aa1</a>.
If this feels familiar, that's because it is &#8211; and the market's playbook has been pretty consistent. The real question now: Will the market freak out for the third time, or has it finally learned to chill?
<h2 class="wp-block-heading">Another 10% Correction Coming?</h2>
Let's rewind.
In August 2011, Standard &amp; Poor's made history by downgrading U.S. debt for the first time ever. The result? A 10.37% drop in the S&amp;P 500 Index over the next 41 trading days, <a href="https://x.com/adamkhootrader/status/1923970924589744439">according</a> to data analyzed by Piranha Profits. But fast forward 12 months, and the index was up 36%. Investors who bought the dip didn't just survive &#8211; they thrived.
Then came August 2023, when Fitch pulled the same move. Same script, different year. The S&amp;P 500 slid 10.31% over 58 trading days. But again &#8211; patience paid off. One year later, stocks were up a cool 37%.
Now, here comes Moody's, joining the downgrade party. And yes, if the market follows precedent, we could be looking at another 10% correction.
Read Also: <a href="https://www.benzinga.com/markets/equities/25/05/45486452/jim-cramer-recalls-2011s-6-7-market-decline-after-us-debt-downgrade-says-it-ultimately-meant-nothing-dan-niles-sees-limited-downside-amid-tariff-rollbacks-fomo">Jim Cramer Recalls 2011&#8217;s 6.7% Market Decline After US Debt Downgrade, Says It &#8216;Ultimately Meant Nothing:&#8217; Dan Niles Sees Limited Downside Amid Tariff Rollbacks, FOMO</a>
<h2 class="wp-block-heading">Bulls Have Reasons To Shrug This One Off &#8211; But Will They?</h2>
But here's the twist &#8211; after two prior false alarms, has Wall Street stopped reacting to credit downgrades like it's the end of the world? After all, these cuts haven't exactly spelled disaster in the long run. Quite the opposite.
And let's not ignore the context: strong earnings from tech giants, resilient consumer spending, and cooling inflation may give bulls a reason to shrug this one off.
But if markets do panic on Monday, history suggests it could be yet another gift-wrapped opportunity to scoop up high-quality stocks at a discount.
Because if there's one thing we've learned, it's this: America's credit rating may slip &#8211; but investor memory tends to fade faster than a market dip lasts.
For investors holding broad S&amp;P 500 ETFs like SPDR S&amp;P 500 ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SPY#NYSE">SPY</a>), iShares Core S&amp;P 500 ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/IVV#NYSE">IVV</a>), and Vanguard S&amp;P 500 ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/VOO#NYSE">VOO</a>), the Moody's downgrade may feel unsettling at first glance &#8211; especially heading into Monday's open. But history offers a useful compass. During the past two U.S. debt downgrades in 2011 and 2023, the S&amp;P 500 fell over 10% within two months, only to surge more than 35% over the following year. If markets follow a similar playbook, any short-term volatility could prove to be a golden buying window for long-term investors. 
In other words, don't be surprised if passive index investors wind up thanking Moody's by this time next year.
Will Wall Street overreact a third time? 
Or has the market finally grown up? 
We'll find out Monday.
Read Next: 
<ul class="wp-block-list">
<li><a href="https://www.benzinga.com/25/05/45488403/moodys-had-an-investment-grade-rating-on-us-debt-during-2008-global-financial-crisis-recent-cut-not-a-huge-shock-says-expert">Moody&#8217;s Had An Investment Grade Rating On US Debt During 2008 Global Financial Crisis: Recent Cut &#8216;Not A Huge Shock,&#8217; Says Expert</a></li>
</ul>
Photo: Shutterstock

Long Ideas

Broad U.S. Equity ETFs

ETFs

S&P 500 History Suggests 10% Drop After Downgrade — Followed By 35% Rally

Wells Fargo analyst Tiago Fauth maintains Inozyme Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/INZY#NASDAQ">INZY</a>) with a Equal-Weight and lowers the price target from $9 to $4.

INZY

Wells Fargo Maintains Equal-Weight on Inozyme Pharma, Lowers Price Target to $4

Good Morning Traders! In today&#8217;s Market Clubhouse Morning Memo, we will discuss SPY, QQQ, AAPL, MSFT, NVDA, GOOGL, META, and TSLA.
Our proprietary formula, exclusive to Market Clubhouse, dictates these price levels. This dynamic equation takes into account price, volume, and options flow. These levels are updated every day and shared with all Clubhouse Members, prior to the opening of the market.
We recommend closely monitoring these stocks, and be prepared to leverage potential breakouts or reversals. As always, stay alert and ready to adjust your tactics based on the market&#8217;s pulse to optimize your trading gains. Now, let&#8217;s dive into the stock analysis:
SPDR S&amp;P 500 ETF Trust (SPY)
The SPY is currently trading around our crucial pivot at 587.31. For a bullish scenario, buyers must drive the price upward toward 589.71 initially. A strong hold above this mark could see bullish momentum pushing further to the significant support area at 592.00. Sustained bullish control above 592.00 during the session might propel prices upward to test the higher level at 593.73. Our ultimate bullish target for today on SPY sits at 595.14.&nbsp;
If the price fails to sustain above the pivotal 587.31, bearish traders will likely step in aggressively toward 585.75. Should selling pressure intensify, we expect a downward push toward 584.68. Breaking through this support convincingly may trigger further declines toward the next major level at 583.18. If market sentiment deteriorates significantly, bears will aim for today&#8217;s ultimate downside target at 581.97.
Invesco QQQ Trust Series 1 (QQQ)
The Q&#8217;s are currently fluctuating near our significant level at 513.64. To achieve bullish momentum, buyers must decisively keep the price above this point. Successful support here can encourage buyers to lift the market toward the critical 515.00 level. If bullish energy continues uninterrupted, we anticipate further upside moves toward the stronger resistance at 516.58. Under strong bullish conditions, today&#8217;s high upside goal for QQQ is marked at 518.65.&nbsp;
Should prices falter at 513.64 during the session, bears will attempt to dominate and swiftly push prices downward toward the immediate level at 511.53. Persistent bearish pressure could result in a deeper decline to test the strength at 509.87. Continued seller momentum may extend losses further toward 508.22. A breakdown below this critical support sets up a test of today&#8217;s low bearish target at 506.68.
Apple Inc. (AAPL)
Apple is presently trading near our key area at 207.93. Bulls will first aim to solidify support slightly higher at 208.81. Successfully holding this mark can fuel a bullish rally towards the next significant upside area at 209.81. Continued buying strength throughout today&#8217;s session could further lift prices toward the prominent resistance at 211.12. If buyers remain firmly in control, our ultimate bullish objective for Apple today lies at 212.44.&nbsp;
If support at 207.93 is compromised during trading, bears will quickly target the downside, first probing at 207.18. Increased selling could lead to further deterioration toward the next downside support at 206.55. If bearish sentiment intensifies, traders will be eyeing the crucial support at 205.54. A breakdown here will likely push prices toward our lowest bearish target for Apple today at 204.33.
Microsoft Corp. (MSFT)
Microsoft is currently positioned around our significant point at 450.26. Bulls must first confirm stability above 453.02, creating favorable conditions for a push upward toward the higher support at 455.77. Consistent buying strength above this point could propel the price higher to test the next resistance area at 457.25. Under continued bullish momentum, the session&#8217;s ultimate bullish goal for Microsoft is situated at 459.18.&nbsp;
Should the market fail to hold support at 450.26, sellers will aggressively target downside levels, initially pressing prices toward 448.18. If selling intensifies, the next area for bearish exploration will be 446.33. Sustained downward pressure could result in a deeper test of support at 444.95. Should this level give way, we anticipate bears pushing Microsoft toward our extreme bearish target today at 442.95.
NVIDIA Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NVDA#NASDAQ">NVDA</a>)
NVIDIA is currently oscillating around the essential level of 131.42. Bulls should first target establishing clear support slightly higher at 132.19. A strong consolidation above this area could ignite further bullish moves upward to 133.31. Persistent buying pressure may result in a further price rise toward 134.56. If bullish sentiment remains high, today&#8217;s highest target for NVIDIA sits at 135.64.&nbsp;
If NVIDIA cannot maintain the critical 131.42 level, bearish traders will push downward aggressively, targeting an initial support test at 129.53. Should this area fail under selling pressure, further declines toward the level at 128.10 can be expected. Weakness continuing to prevail could bring prices to challenge the important support at 126.84. Under heavy selling pressure, bears may reach today&#8217;s extreme bearish target of 125.21.
Alphabet Inc Class A (GOOGL)
Alphabet is currently trading near our primary level at 163.79. For bullish traders, the immediate objective is establishing strong support at 165.41. Successfully holding this level can enable further upside momentum, targeting 167.04 next. Continued bullish activity today can potentially push prices toward our top bullish target at 169.34.&nbsp;
If support at 163.79 falters, sellers will aim lower toward 161.79. A breakdown here could drive prices further downward to initially test 160.36. Strong and persistent selling would likely encourage bears to challenge deeper support levels, bringing today&#8217;s bearish target of 158.54 firmly into focus.
Meta Platforms Inc (META)
Meta is currently trading near our critical pivot at 629.88. Bullish momentum requires first reclaiming support clearly above 635.49, potentially triggering further upward moves toward 642.59. A sustained bullish environment could propel the price toward the notable resistance at 646.48. Continued bullish pressure may help Meta reach today&#8217;s highest bullish objective at 650.56.&nbsp;
If 629.88 fails as a stable support today, bears will aggressively press prices downward, targeting 622.01. Continued bearish force can drive prices further toward the lower level at 615.65. Significant selling pressure could cause a deeper drop, testing today&#8217;s ultimate bearish goal of 609.30.
Tesla Inc. (TSLA)
Tesla is currently trading near our vital reference level of 333.93. For a bullish scenario, buyers must initiate momentum higher toward 340.97. Sustained strength above this point could further lift prices to test resistance at 346.64. If the broader market rallies significantly today, Tesla may see an extended upside move to 350.87. Continued bullish enthusiasm could propel prices toward today&#8217;s highest target for Tesla at 356.80.&nbsp;
If Tesla cannot hold the crucial level of 333.93, bears will target downward momentum immediately toward 327.59. Persistent selling can lead to a further decline toward the next significant support at 322.52. Should bearish pressure remain intense, the critical lower support at 315.93 could be challenged, potentially extending losses toward today&#8217;s extreme bearish target of 312.42.
Final Word:&nbsp;
Today&#8217;s economic calendar is notably sparse. At 10:00 AM ET, we have the release of April&#8217;s Leading Index, providing minimal market-moving potential. Traders will, however, closely monitor commentary from Federal Reserve speakers, including Bostic, Williams, and Jefferson, all scheduled prior to market open, and Logan at 1:15 PM ET and Kashkari at 1:30 PM ET. With limited economic catalysts, heightened market attention will be directed toward recent developments surrounding Moody&#8217;s credit rating downgrade and ongoing tariff negotiations.&nbsp;
In the current market environment characterized by lower economic data visibility, expect heightened volatility around headlines. Traders should stay vigilant and prioritize risk management strategies to safeguard against unexpected market swings. Stay disciplined and best of luck today!
The Morning Memo is curated by RIPS, a pro trader with years of experience in equities, options, and futures trading. RIPS is at the heart of the exclusive Market Clubhouse community, offering his insights, expertise, and real-time mentorship.
Start your day with a live daily market analysis, a carefully selected watch list, early access to the Morning Memo, and exclusive Market Clubhouse price levels, providing precise support and resistance indicators. When you become a member of Market Clubhouse, you will gain early access to the Morning Memo, just like this one, every single day—hours before it's published. You will also have access to a live stream with zero latency and screen sharing, enabling you to witness Rips executing his trades in real-time and sharing his exclusive trading plans, strategies, and live decision-making.
For a limited time during our special promotion, you can join RIPS and get a full access pass to Market Clubhouse for 7 full days for just $7. Check it out at <a href="https://marketclubhouse.club/7Days/" title="https://marketclubhouse.club/7Days/">https://marketclubhouse.club/7Days/</a> where you can trade live with him and tap into his wealth of knowledge and experience. You can also catch Rips on his live day trading streams every Monday-Friday at 8 am EST on the Market Clubhouse YouTube channel: <a href="https://www.youtube.com/@MarketClubhouse" title="https://www.youtube.com/@MarketClubhouse">https://www.youtube.com/@MarketClubhouse</a>.

Technicals

Opinion

Signals

Markets

NVDA

How To Trade SPY And Top Tech Stocks Using Technical Analysis

Evercore ISI Group analyst David Raso maintains Deere (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/DE#NYSE">DE</a>) with a In-Line and raises the price target from $455 to $493.

Evercore ISI Group Maintains In-Line on Deere, Raises Price Target to $493

Washington State Approves JinkoSolar's EAGLE Preserve Program For Its 1st Module Strewardship Program.

Blackboxstocks Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BLBX#NASDAQ">BLBX</a>), ("Blackbox" or the "Company"), announces that its merger target REalloys Inc. ("REA" or "REalloys"), has signed a joint Memorandum of Understanding ("MOU") with the Saskatchewan Research Council ("SRC") to begin working together to advance REA's initiative of commercial production of high-performance rare earth magnet materials. REA's planned production starts in Q2, with targeted expansion to 500 metric tonnes ("mt") per year of magnet materials in 2026, and 1,000 mt by 2028.&nbsp;&nbsp; This is a major milestone to achieve the objective of a secure &amp; resilient North American magnet materials &amp; magnets supply chain focused on demand from U.S. Protected Markets (includes: National Defense Stockpiles ("NDS"), Defense Industrial Base ("DIB"), Nuclear Industrial Base ("NIB"), Robotics, Electric Aviation, Critical Infrastructure industries, and for U.S. Partner Countries with Defense Treaties, Alliances &amp; Agreements).
By combining REA's mid-stream production capabilities in heavy rare earth dysprosium-terbium ("DyTb") metals with SRC's mid-stream production capabilities in light rare earth neodymium-praseodymium ("NdPr") metals, high performance magnet materials can now be made in North America, at REA's Euclid, Ohio facility, to supply U.S. Protected Markets.

BLBX

Blackboxstocks' Merger Target REalloys Signs Joint MOU With Saskatchewan Research Council To Begin Working Together To Advance REA's Initiative Of Commercial Production Of High-Performance Rare Earth Magnet Materials

Evercore ISI Group analyst Steve Sakwa maintains Cousins Props (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CUZ#NYSE">CUZ</a>) with a In-Line and raises the price target from $30 to $31.

Evercore ISI Group Maintains In-Line on Cousins Props, Raises Price Target to $31

Skillful Craftsman Education Technology Limited ("Skillful Craftsman" or the "Company") (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/EDTK#NASDAQ">EDTK</a>), a company focused on advancing technological innovation in education through the digital transformation of educational institutions, today announced new business initiatives designed to propel the Company's growth.

EDTK

Skillful Craftsman Education Technology Launches New Business Initiatives To Drive Growth And Advance Digital Transformation In Education

Management

BBWI

Bath & Body Works Appoints Daniel Heaf As CEO

Evercore ISI Group maintains CNH Industrial (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CNH#NYSE">CNH</a>) with a In-Line and raises the price target from $13 to $15.

Evercore ISI Group Maintains In-Line on CNH Industrial, Raises Price Target to $15

The Board of Directors of MVB Financial Corp. ("MVBF" or "MVB Financial") (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MVBF#NASDAQ">MVBF</a>) today announced the authorization of a stock repurchase program of up to $10 million of MVB's common stock.
MVB intends to begin repurchasing stock in May 2025, and the stock repurchase program will expire upon the expenditure of $10 million, when terminated or otherwise completed. Purchases may be made in open-market transactions, in block transactions on or off an exchange, in privately negotiated transactions or by other means as determined by MVB's management and in accordance with the regulations of the Securities and Exchange Commission. The timing of purchases and the number of shares repurchased under the stock repurchase program will depend on a variety of factors including price, trading volume, market conditions and corporate and regulatory requirements.

Buybacks

MVBF

MVB Financial Corp. Announces The Authorization Of A Stock Repurchase Program Of Up To $10M Of Common Stock

Paramount Group, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/PGRE#NYSE">PGRE</a>) ("Paramount" or the "Company") announced today that its Board of Directors has initiated a review and evaluation of strategic alternatives to maximize shareholder value. The announcement follows a successful first quarter marked by strong leasing activity.

PGRE

Paramount Group Announces Strategic Alternatives Review To Maximize Shareholder Value

Lifeward Ltd. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LFWD#NASDAQ">LFWD</a>) ("Lifeward" or the "Company"), a global leader in innovative medical technology to transform the lives of people with physical limitations or disabilities, today announced that Mark Grant has been appointed as the Company's new President and Chief Executive Officer, effective June 2, 2025. Larry Jasinski, Lifeward's outgoing CEO, will serve as Co-CEO and, as previously announced, will serve in an advisory capacity until the end of June to assist with the transition, and thereafter on an as-needed basis through the end of 2025.

LFWD

Lifeward Appoints Mark Grant As President And CEO, Effective June 2, 2025

-- First ever clinical data supporting safety and efficacy of Prime Editing in humans --
-- Initial data from first patient dosed in Phase 1/2 trial finds single dose of PM359 led to 58% DHR positivity by Day 15 and 66% by Day 30, well above levels believed to be potentially curative --
-- Rapid engraftment observed in both neutrophils and platelets --
-- Encouraging safety profile; no serious adverse events related to PM359 --
-- Initiating efforts to explore continued clinical development opportunities for PM359 external to Prime Medicine --
CAMBRIDGE, Mass., May 19, 2025 (GLOBE NEWSWIRE) -- Prime Medicine, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PRME#NASDAQ">PRME</a>), a biotechnology company committed to delivering a new class of differentiated one-time curative genetic therapies, today announced positive initial data from the first patient dosed in its ongoing Phase 1/2 clinical study of PM359 in Chronic Granulomatous Disease (CGD). Preliminary results from the first patient demonstrated that PM359 was well-tolerated, showed rapid engraftment and restored NADPH oxidase activity to well above the threshold for clinical benefit, as measured by the dihydrorhodamine (DHR) assay.
CGD is a rare inherited disease that leads to recurrent, debilitating and often life-threatening infections. It is caused by mutations in genes, including&nbsp;NCF1, that encode proteins that form the NADPH oxidase complex, an enzyme that kills bacteria and fungi to control infection. PM359, an ex vivo Prime Edited autologous hematopoietic stem cell (HSC) product for the treatment of p47phox CGD and the first Prime Editor generated therapy to be administered in humans, is designed to correct the delGT mutation in NCF1, the most prevalent disease-causing mutation in the p47phox variant of CGD, thereby addressing its underlying pathophysiology. Prime Medicine estimates that CGD causative mutations occur in between one in 100,000 and one in 200,000 births in the United States, with approximately 25 percent of patients presenting with the p47phox form of the disease.

Biotech

General

PRME

Prime Medicine Announces Initial Data From First Patient Dosed In Phase 1/2 Trial Finds Single Dose Of PM359 Led To 58% 'DHR Positivity' By Day 15 And 66% By Day 30, Well Above Levels Believed To Be Potentially Curative

Hong Kong leading logistics solutions provider New Century Logistics (BVI) Limited (hereinafter referred to as "New Century") today announced the formal signing of a Memorandum of Understanding ("MOU") with Silk Way Airlines Limited (hereinafter referred to as "Silkway"), a well-known air cargo airline in Hong Kong. Both parties will explore innovative solutions in the international air freight logistics sector based on resource sharing and complementary strengths, aiming to enhance global supply chain efficiency for their clients.
Stronger collaboration
According to the MOU, New Century and Silkway will conduct in-depth cooperation in the following directions:
<ul>
<li>Joint development of international air freight logistics solutions: integrating New Century's global logistics network with Silkway's air cargo resources to provide end-to-end efficient transportation services for cross-border trading enterprises.</li>
<li>Market intelligence and logistics best practices sharing: optimize route planning, cost control and risk management capabilities through data exchange and experience sharing.</li>
<li>Collaborative marketing and brand promotion: Joint promotion of services offered by both parties to expand business coverage in Asia Pacific, Europe and emerging markets.</li>
<li>Customer experience upgrade: build a seamless logistics service system, improve the transparency of cargo tracking and delivery timeliness.</li>
</ul>

NCEW

New Century Logistics Signs MOU With Silk Way Airlines To Explore Innovative Solutions In International Air Freight Logistics Sector

Wells Fargo analyst Praneeth Satish maintains Nextracker (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NXT#NASDAQ">NXT</a>) with a Overweight and raises the price target from $69 to $71.

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