| Oct 12, 2026 | Robert Blum | PRESIDENT & CEO | SELL-OPTIONS | — | $36.74 | $392K |
| Oct 6, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $34.59 | $188K |
| Sep 28, 2026 | Robert Blum | PRESIDENT & CEO | SELL-OPTIONS | — | $38.03 | $411K |
| Sep 22, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $38.05 | $212K |
| Sep 15, 2026 | Robert Landry | DIRECTOR | SELL | 1.000K | $72.13 | $72K |
| Sep 14, 2026 | Robert Blum | PRESIDENT & CEO | SELL | 99.276K | $40.11 | $7.3M |
| Sep 11, 2026 | Robert Landry | DIRECTOR | SELL | 1.000K | $74.66 | $75K |
| Sep 8, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $41.63 | $237K |
| Sep 1, 2026 | LYNNE PARSHALL | DIRECTOR | SELL | 5.000K | $71.48 | $357K |
| Aug 31, 2026 | Andrew Callos | EVP, CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $46.75 | $470K |
| Aug 31, 2026 | Robert Blum | PRESIDENT & CEO | SELL-OPTIONS | — | $40.42 | $447K |
| Aug 18, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $41.81 | $238K |
| Aug 10, 2026 | Robert Blum | PRESIDENT & CEO | SELL-OPTIONS | — | $43.68 | $496K |
| Jul 30, 2026 | Andrew Callos | EVP, CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $51.57 | $793K |
| Jul 27, 2026 | Robert Blum | PRESIDENT & CEO | SELL-OPTIONS | — | $45.73 | $527K |
| Jul 21, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $44.20 | $255K |
| Jul 13, 2026 | Robert Blum | PRESIDENT & CEO | SELL | 10.000 | $46.31 | $536K |
| Jul 7, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $47.21 | $276K |
| Jul 1, 2026 | Robert Blum | PRESIDENT & CEO | SELL | 7.500K | $84.92 | $637K |
| Jul 1, 2026 | Andrew Callos | EVP, CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $54.53 | $938K |
| Jul 1, 2026 | Sung Lee | EVP, CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $68.15 | $44K |
| Jun 29, 2026 | Sung Lee | EVP, CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $65.42 | $123K |
| Jun 24, 2026 | Sung Lee | EVP, CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $64.70 | $1.4M |
| Jun 23, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $43.66 | $251K |
| Jun 15, 2026 | Robert Blum | PRESIDENT & CEO | SELL | 7.500K | $70.46 | $528K |
| Jun 9, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $37.89 | $211K |
| Jun 1, 2026 | Dr. Kaye | DIRECTOR | SELL | 2.933K | $76.09 | $223K |
| Jun 1, 2026 | Andrew Callos | EVP, CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $48.67 | $762K |
| Jun 1, 2026 | LYNNE PARSHALL | DIRECTOR | SELL | 5.000K | $74.08 | $370K |
| May 27, 2026 | Robert Blum | PRESIDENT & CEO | SELL | 7.500K | $77.21 | $579K |
| May 19, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $41.74 | $238K |
| May 14, 2026 | Robert Blum | PRESIDENT & CEO | SELL | 7.500K | $77.92 | $584K |
| May 5, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $42.59 | $243K |
| May 5, 2026 | Dr. Wierenga | DIRECTOR | SELL-OPTIONS | — | $43.70 | $252K |
| May 5, 2026 | Sung Lee | EVP, CHIEF FINANCIAL OFFICER | SELL | 23.906K | $76.87 | $1.8M |
| May 5, 2026 | Dr. Henderson | DIRECTOR | SELL-OPTIONS | — | $41.79 | $1.4M |
| May 5, 2026 | Andrew Callos | EVP, CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $58.19 | $432K |
| May 1, 2026 | Andrew Callos | EVP, CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $51.31 | $434K |
| Apr 30, 2026 | Andrew Callos | EVP, CHIEF COMMERCIAL OFFICER | SELL-OPTIONS | — | $43.26 | $600K |
| Apr 29, 2026 | Robert Blum | PRESIDENT & CEO | SELL | 7.500K | $59.62 | $447K |
| Apr 21, 2026 | Dr. Malik | EVP RESEARCH & DEVELOPMENT | SELL-OPTIONS | — | $36.74 | $203K |
